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KMID : 0363219740120040233
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Korean Journal of Dermatology
1974 Volume.12 No. 4 p.233 ~ p.236
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Influence of Descresept^® on Clinical Course and Phagocytic Function of Neutrophils in Atopic Dermatitis
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Abstract
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The study was undertaken to evaluate the phagocytic function of polymorphonuclear leukocyte correlated with clinical appearance following Descresept^(®)(aristolochic acid) administration in 11 patients with atopic dermatitis.
Nitroblue tetrazolium dye reduction test was done as weekly interval, including before and after oral Descresept^(®) and the method was essentially same with that of original Park et al. The results are as follows.
1. In 6 of 11 patients, clinical improvement was accompanied by increasing NBT scores. The clinical improvement was first noted in about 1 week after starting of oral Descresepe^(®).
2. In 2 of 11 patients, clinical aggravation was noted inspite of Descresept administration. Increase in dosage of Descresept^(®) made clinical improvement with increasing NBT scores.
3. In 3 of the 11 patients, there was clinical improvement, but NBT scores weres slightly decreased.
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